Atopica®

Product contains:

Cyclosporine

Product indications:

Atopica® is indicated to control atopic dermatitis in dogs

Dosage and administration:

The initial daily dose of Atopica is 5 mg/per kg/per day (3.3-6.7 mg/kg/day) as a single daily dose for 30 days, or as otherwise directed by your veterinarian.
Following the initial daily treatment period, the Atopica dose may be tapered by decreasing the dosing frequency to every other day or twice a week, to maintain the desired therapeutic effect.
Atopica should be given at least one hour before, or two hours after a meal. If a dose is missed, the next dose should be administered (the standard amount) as soon as possible. However dosing should be no more frequent than once daily.

Warnings, side effects and potential drug interactions:

Atopica is contraindicated for use in dogs with a history of malignant tumors.
Gastrointestinal problems and gum overgrowth may occur at the initial recommended dose.
Atopica should be used with caution if given concurrently with medications which affect the metabolism of the drug in the liver as this may lead to increased plasma levels of cyclosporine and an increased risk of toxic effects.
The safety and effectiveness of Atopica has not been established in dogs less than six months old, or weighing less than four pounds.
Atopica is not for use in breeding dogs, pregnant or lactating females.
There have been reports of convulsions in human patients receiving cyclosporine, particularly in combination with a high dose of methylprednisolone (a corticosteriod).
Killed vaccines are recommended for dogs receiving Atopica, as the impact the drug has on the immune response to modified live vaccines is unknown.
Diarrhea, vomiting, ear infections, urinary tract infections, anorexia, gum overgrowth, enlarged lymph nodes, depression, excessive drinking and urinating, soft stools, seizures, itching, red skin, nausea, regurgitation, constipation and flatulence have been seen in association with cyclosporine therapy. Of these, vomiting and diarrhea are the most common adverse reactions. In overseas countries, acute collapse, pale mucous membranes and delayed capillary refill time, weakness, and diarrhea with blood have also been noted.

Storage:

Atopica should be stored and dispensed in the original unit-dose container at controlled room temperature between 59 and 77°F (15-25°C).

Manufacturer:

Novartis Animal Health US, Inc.
3200 Northline Ave, Suite 300, Greensboro, NC, 27408

NADA # 141-218 , approved by the FDA

Federal law restricts this drug to use by or on the order of a licensed veterinarian.